医学研究生陈阳遭仇敌杨健与前女友廖莹莹联手陷害，不仅被设计变成“傻子”，还被李梅诱骗、赵老三殴打致昏迷。昏迷中，他意外被神秘女子苏玉所救，更获得传承玉佩，自此踏上修炼与医术并行的逆袭之路。
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全30集假盲人按摩师王美丽为西蒙娜上门按摩却看到了罗宾的被害现场。为了活命她假装盲人骗过来多番试探。但西蒙娜后来的再次试探，暴露了女主看到凶案现场的事实。在王美丽将死之际，余圆的出现打破了僵局。局面几次扭转，西蒙娜才得知这一切目的竟是女主为了。
全30集天医堂少主陆玄遭遇打劫深受重伤，被路过的陈家家主所救，为了报恩答应其留在陈家效力并根治陈家小姐陈曼妮的衰老症，三年来他兢兢业业让陈氏扬名中外，陈曼妮的重症也即将治愈，但是不知陆玄真实身份的陈曼妮屡屡刁难，不甘受辱的陆玄待三年期到便离开返回天医堂，失去陆玄救治的陈曼妮衰老症再度发作，为了救治也求到天医堂门下，却不知现在天医堂的主事人正是被她嫌弃赶走的陆玄。
7.0全70集心理咨询师陆之曼，因妹妹跳楼身亡，从遗物锁定大夏集团顾乘风为嫌疑人。她借集团心理疏导接近顾乘风复仇，却结识其弟顾破云。周旋间，她发现妹妹死亡有隐情，复仇路偏离预想。
6.0全59集上世纪九十年代，濒临倒闭的大风厂厂长周拓突患阿尔兹海默症，他隐瞒病情拒绝治疗，决心在记忆消失前完成工厂改组，为工人保住饭碗，为妻女留下财产。然而妻子与白月光会计的暧昧、工人的误解与羞辱接踵而至，周拓默默承受，甚至促成妻子与他人感情。当真相被医生揭露时，众人陷入悔恨，却又在流言中质疑真假。最终，当记忆彻底消散，留给所有人的是无尽的愧疚与迟来的醒悟……
全60集社畜苏默默猝死穿越却天崩开局，被卖青楼逃跑，却撞上命不久矣的太子，与太子意外接触竟救活太子，面对几方势力夹击，苏默默化身三面间谍，凭借智慧，巧施妙计帮助太子化险为夷，最终赢得皇帝的认可，与太子成婚。
全66集周志刚临终前亲眼目睹妻子公开在电视上感谢其红颜知己，而女儿更是直言想他早死给赵叔叔让位。重活一世，周志刚心死，签下离婚书，远赴西北参加机密科研，后收养烈士遗孤，与青梅竹马重组家庭，与前妻母女永不相见。
全84集新婚夜，女主被深爱十多年的男人推入火海，他恨她害死白月光，蛰伏多年只为杀她。濒死时女主被京圈大佬所救。重生后，她解除婚约，接近大佬纠缠情感，还揭露了青梅竹马隐忍复仇的真相。
全83集叶初见和云逸因为一场车祸造成二人分开，二人在机缘巧合下，再次重新相爱，然而，叶初见的父亲之所以安排女儿相亲，实际上是为了让自己的私生子拥有唯一继承权，二人携手，将叶家的一切阴谋粉碎。
全74集方亦宸为追寻纯粹感情，隐瞒身份在工地打工五年，攒下30万彩礼准备迎娶苏郁。然而苏郁在王昊的诱惑下背叛婚约，与其母李蓉当众羞辱方亦宸是“穷酸农民工”，苏郁更怒扇方亦宸并宣告分手。
7.0全50集叶婉是一名嫉恶如仇的武术教练，从她手里带出了多个武术冠军，在和本市著名的宠物医生纪森相亲后，两人迅速闪婚。因为担心自己的职业会给对方造成心理负担，叶婉对外宣称自己是幼师。
全80集绝症少女唐晚意外觉醒穿越技能，为续命每天“闪现”到暴君陆渊寝宫吸龙气。从互坑互杀到联手，她用现代泡面、科技助力，两人情愫暗生。却因预言诀别，看他们如何沙雕互怼、甜虐交织地跨越时空相爱相杀。