秦疏瑕从小被家族认定为灾星，一次意外她有了南诏国太子东方衍的孩子。后被姐姐和母亲囚禁取子。幸而为神医所救，七年后为给小儿子治病，她重回南昭国，将秦家母女的阴谋戳破，在儿子们的助攻下与东方衍终成眷属。
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全31集女主在事业成就风生水起之时嫁给了自己丈夫，结婚后丈夫却一直冷落她和另外一个女人暧昧不清，甚至自己的亲生女儿也向着小三，忍受了6年后终于看清现实，离开这个家庭，当女主展现自己真实实力后，丈夫后悔莫及。。。
10.0全81集马英辅佐皇帝打下天下，与皇帝伉俪情深，皇帝亲切的喊她妹子，与她共治天下，两人约定前朝归皇帝，后宫及王族贵胄归皇后打理。马皇后爱民如子倡行节俭，连自己的凤牌都用镀金的木牌，但她万万没想到，自己娘家人会打着自己的旗号贪赃枉法，皇帝碍于皇后的面子睁一只眼闭一只眼，对此马皇后忍无可忍决定回乡省亲，收拾这帮贪官污吏。
全70集苏清禾，苏家亲生女，天医门准门主，因药神命格被弃，下山寻亲。苏家偏养女苏清婉，其借药神系统抄苏清禾药方并诬陷她。全城瘟疫时，苏清禾遭诬陷致死，重生后决心查明真相，让众人血债血偿。
10.0全70集沈清秋全家被少帅桑北淮虐杀，她化身六姨太入帅府复仇。后宅毒计环生，沈清秋以命破局，与浪荡二少爷桑宴结成危险同盟，终将诛恶扫净。也与桑宴在算计中孽情丛生。最终，沈清秋与放弃权位的桑宴一同出走，远离囚笼。
8.0全80集桑鹿觉醒为豪门虐文恶毒女配，拒被剧情操控，主动亲近哑巴丈夫封砚，以 “喇叭” 属性破冰。治愈他开口，化解家族矛盾，打脸反派，智斗绿茶，逆袭成真女主，众人挣脱原著，开启反套路人生。
10.0全73集许烟雨和沈煜、陆亦枫是三人约定等正式工作以后，许烟雨要从两人中选择一个跟他结婚共度余生，可是心机女阮星遥突然插足三人感情，把自己塑造成一个柔弱无知的小白兔形象，其实暗地里对许烟雨各种欺辱和霸凌。
7.0全74集顾家嫡女顾盈盈不愿嫁权势滔天的九千岁邵若安，设计让外室之女顾芷瑶替嫁。顾芷瑶与邵若安从误会到相知，却屡遭顾盈盈和太后的陷害。顾芷瑶为救邵若安因伤重离世。邵若安悔恨不已，自尽于顾芷瑶墓前，两人以死相守。
9.0全75集状元糟糠之妻供夫考取功名、养孩子。丈夫高中后接寡嫂及侄子侄女进京，五年间女主仅收十五封书信无钱米。灾荒年她割肉为药引换馒头仍失孩子，此时锦衣丈夫与大嫂出现，她醒悟海誓山盟是假，悲愤吐血而亡。
全60集何枝和池墨是一对在娱乐圈底层摸爬滚打的小透明情侣，何枝一步步助夫成影帝后，却和爱人越走越远，更是被爱人误解，被网友网暴，直到何枝死后，何枝的日记本被公开，人们才知道，何枝这辈子只甜过那一刻。
全67集女主沈皖仪本是现代女子，在祖奶奶墓前许愿求完美老公时，意外穿越成了虐男主养子的恶毒女配。为了改写命运，她开始讨好养子秦晏晏。此时，她偶遇因蛊毒变成小孩的男主秦怀州。沈皖仪不知对方身份，对这个 “小团子” 百般逗弄，而秦怀州昼夜切换形态，两人阴差阳错同眠，情愫也在悄然间暗生。原书女主姜羡宁为了破坏他们，挑拨离间，唆使秦晏晏使坏并诬陷沈皖仪下毒。好在秦怀州看似冷漠，实则多次暗中相护，关键时刻更是为她揭穿阴谋。随着蛊毒逐渐消除，两人从最初的试探走向真心，共同对抗反派，携手重建温暖家庭